Welcome to the eCancerTrials.com National Cancer Clinical Trials Database. When you or a loved one are diagnosed with cancer, knowing every treatment option available is your first step in receiving the most complete care. Your treatment plan may include choosing to participate in a cancer clinical trial. Clinical trials in cancer are research studies designed to evaluate new cancer treatment, management, and prevention options. Clinical trials conducted with cancer patients evaluate the safety and effectiveness of new or modified cancer treatment strategies. New anticancer drugs, unique approaches to surgery and radiation therapy are used as well as various combinations of cancer treatments.

Many medical professionals encourage those diagnosed with cancer to at least consider participating in a clinical trial in addition to other treatment options. Furthermore, many treatment options for cancer patients are only available through clinical trials, making participation in a trial the only way to access certain therapies. So if you are not evaluating potential cancer treatments accessible through the clinical trials process alongside current standard therapies, you're not weighing all of your available options.

Although there is currently no single, comprehensive source of available clinical trials, eCancerTrials.com’s provides information on more than 2,000 clinical trials being conducted by leading cancer researchers from all 50 states. These clinical trials evaluate novel treatment approaches and new cancer drugs in all major cancer types, including breast cancer, colon cancer, prostate cancer, lung cancer, lymphoma, leukemia, and many others.

eCancerTrials.com is a free and confidential cancer clinical trials matching and referral service. This resource is provided to cancer patients and their caregivers by leading cancer information specialists at CancerConsultants.com. Interested patients and their advocates may use this resource to:

• Search—free of charge—for clinical trials applicable to your situation.
• Search without sharing personal information until you find a trial that is appropriate. At this point you can directly call or e-mail the cancer clinic or center conducting the trial. In this manner your privacy is respected and ensured.
• eCancerTrials.com provides interested patients and their family members with additional services to help locate appropriate clinical trials.

Use the search engine below to look for clinical trials, or learn more about clinical trials.

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Displaying clinical trials in "Colorectal Cancer" in "All cancer stages" in "All States":

Protocol No.	Title
CTSUN0147	A Randomized Phase III Trial of Oxaliplatin Plus 5-FU/Leucovorin with or without Cetuximab after Curative resection for Patients with Stage III Colon Cancer.
ARD5099	A Randomized, Prospective Study Comparing Three Regimens of Eloxatin™ Plus Fluoropyrimidine For Evaluation of Safety and Tolerability of Patients With Advanced Colorectal Cancer (TREE STUDY)
RTOG0822	A Phase II Evaluation of preoperative Chemoradiotherapy utilizing intensity modulated radiation therapy (IMRT) in combination with Capecitabine and Oxaliplatin for patients with locally advanced rectal cancer.
CPTAIV-0020-411	A Randomized, Multi-center Phase III Trial of Irinotecan in Combination with Three Different Methods of Administration of Flouropyrimidine: Infusional 5-FU (FOLFIRI), Bolus 5-FU (Day 1 and *), and Oral Capecitabine (Day 1-14); with Celecoxib Versus Placebo as First-Line Treatment for Patients with Metastatic Colorectal Cancer
REFMAL39	A Phase I, Open-Label, Dose-Escalation Study of SB-715992 Administered Weekly for Three Consecutive Weeks of 28-Day Cycle in Patients with Solid Tumors
CPTK7870135-306241	A randomized, double-blind, placebo-controlled, phase III study in patients with metastatic adenocarcinoma of the colon or rectum who are receiving first-line chemotherapy with oxaliplatin/5-fluorouracil/leucovorin and PTK787/ZK 222584 or placebo
G200502	Double-blind, placebo-controlled, dose-finding study of the effect of GTx-024 on muscle wasting (cachexia) in patients with cancer.
GenentechAPO4565g	A Phase Ib Study of the Safety and Pharmacokinetics of Apo2L/TRAIL Administered in Combination with the Folfox Regimen and Bevacizumab in Patients with Previously Untreated, Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
07-141	A Multi-center, Open-label, Randomized, Phase 2 Clinical Trial Evaluating Safety and Efficacy of FOLFIRI with Either Panitumumab or Bevacizumab as a Second-line Treatment in Subjects with Metastatic Colorectal Cancer
B-1-08(ECOG5202)	A Randomized, Phase III Study comparing 5-FU, Leucovorin and Oxaliplatin versus 5-FU, Leucovorin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers.
ML18491	Xelox-A-DVS: A Randomized Study of Intermittent Capecitabine in Combination with Oxaliplatin (XELOX Q3W) and Bevacizumab versus Intermittent Capecitabine in Combination with Oxaliplatin (XELOX Q2W) and Bevacizumab as First-Line Treatment for Patients with Metastatic Colorectal Cancer
DU-1-07	A Multi-Center, Open-Label, Randomized, Phase III Trial Evaluating Safety and Efficacy of FOLFIRI with either Panitumumab or Bevacizumab as a Second-Line Treatment in Subjects with Metastatic Colorectal Cancer.
CTSUE5202	A randomized phase III clinical trial comparing 5-fluorouracil (5-FU), Leucovorin, Oxaliplatin (mFOLFOX6) and Bevacizumab in patients with stage II colon cancer at high risk for recurrence to determine prospectively the prognostic value of molecular markers.
E5204	Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil and Leucovorin vs Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-operative chemoradiation
USO05-102	A Randomized Phase 2 Trial of Pre-Operative Chemoradiotherapy with or without Cetuximab(ERBITUX) in Locally Advanced Adenocarcinoma of the Rectum.
USO06-078	A Multi-center, Open-Label, Single-Arm Trial Evaluating Panitumumab in Combination with FOLFRI Therapy Following First-Line FOLFOX and Bevacizumab Treatment of Metastatic Colorectal Cancer
Calgb80405	A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
USOR08111	A Phase 1b/2 Study of AMG 655 in Combination with Modified FOLFOX6 and Bevacizumab for the First-Line Treatment of Subjects with Metastatic Colorectal Cancer
C80405	A Phase III Trial of Irinotecan/5-FU/Leucovorin or Oxaliplatin/5-FU/Leucovorin with Bevacizumab, or Cetuximab (C225), or with the Combination of Bevacizumab and Cetuximab for Patients with Untreated Metastatic Adenocarcinoma of the Colon or Rectum
20060141	A Multi-center, Open-label, Randomized, Phase 2 Clinical Trial Evaluating Safety and Efficacy of FOLFIRI with Either Panitumumab or Bevacizumab as Second-line Treatment in Subjects with Metastatic Colorectal Cancer.
REFMAL31	A STUDY TO DETERMINE THE BIOEQUIVALENCE OF AN ORAL FORMULATION OF TOPOTECAN CONTAINING THE DRUG SUBSTANCE MANUFACTURED BY NEW PROCESS RELATIVE TO THE CURRENT STUDY FORMULATION OF TOPOTECAN IN PATIENTS WITH ADVANCED SOLID TUMORS
REFMAL32	AN OPEN-LABEL, SAFETY, PHARMACOKINETIC AND PHARMACODYNAMIC STUDY OF MULTIPLE DOSES OF GW572016 TO EXAMINE THE INHIBITION OF EGFR/ERBB-2 PHOSPHORYLATION IN CANCER PATIENTS WITH SOLID TUMORS
REFMAL33	A PHASE I TRIAL OF WEEKLY AMONAFIDE (AMF)IN PATIENTS WITH ADVANCED, SOLID TUMORS
REFMAL34	A PHASE I STUDY OF TOPOTECAN IN COMBINATION WITH DOCETAXEL IN PATIENTS WITH REFRACTORY AND/OR ADVANCED SOLID TUMORS
MCC13449	A Multicenter Trial for Microarray Analysis of Colon Cancer Outcome-A.
20050184	A Phase 2, Open-label, Randomized Clinical Trial of Skin Toxicity Treatment in Subjects Receiving Second-line FOLFIRI or Irinotecan Only Chemotherapy Concomitantly with Panitumumab.
AVF3991n	An observational study of Avastin (Bevacizumab) in combinations with chemotherapy for treatment of metastatic or locally advanced and unresectable colorectal cancer, locally advanced or metastatic non-small cell lung (excluding predominant squamous cell histology), or locally recurrent or metastatic breast cancer.
NCCTGN0147	A Randomized Phase III Trial of Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) with or without Cetuximab (C225)after Curative Resection for Patients with Stage III Colon Cancer.
3304C	A Phase II trial using a combination of Oxaliplatin, Capecitabine, and Celecoxib with Concurrent Radiation for Patients with Newly diagnosed Resectable Rectal Cancer
EFC10262	A Multinational, Randomized, Double-blind Study, comparing the Efficacy of Aflibercept Once Every 2 Weeks Versus Placebo in Patients with Metastatic Colorectal Cancer (MCRC) Treated with Irinotecan / 5-FU Combination (FOLFIRI) after failure of an oxaliplatin based regimen
SWOGS0600	SWOG S0600: Phase III Trial of Irinotecan-based Chemotherapy plus Cetuximab (NSC-714692) with or without Bevacizumab (NSC-704865) as Second-Line Therapy for Patients with Metastatic Colorectal Cancer Who Have Progressed On Bevacizumab with Either Folfox, Optimox or Xelox
BRITE	An Observational Study of Avastin (Bevacizumab) in Combination with Standard Chemotherapy for First-Line Treatment of Metastatic Colorectal Adenocarcinoma
EZN-2208-04	A Phase 2 Study of EZN-2208 (PEG-SN38) Administered With or Wothout Cetuximab in Patients with Metastatic Colorectal Carcinoma (mCRC)
NSABPR-04	A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with Preoperative Radiation and Continuous Intravenous Infusion (CVI) of 5-Fluorouracil (5-FU) in the Treatment of Patients with Operable Carcinoma of the Rectum
Amgen20070509	A Randomized, Multicenter, Phase 2 Study to Compare the Efficacy of Panitumumab in Combination with mFOLFOX6 to the Efficacy of Bevacizumab in Combination With mFOLFOX6 in Patients With Previously Untreated, KRAS Wild-Type, Unresectable, Metastatic Colorectal Cancer
SWOGC80405	A PHASE III TRIAL OF IRINOTECAN /5-FU/ LEUCOVORIN OR OXALIPLATIN/ 5-FU/ LEUCOVORIN WITH BEVACIZUMAB, OR CETUXIMAB (C225), OR WITH THE COMBINATION OF BEVACIZUMAB AND CETUXIMAB FOR PATIENTS WITH UNTREATED METASTATIC ADENOCARCINOMA OF THE COLON OR RECTUM
REFMAL29-CR	A PHASE I STUDY TO DETERMINE THE SAFETY AND PHARMACOKINETICS OF BMS-387032 GIVEN EVERY THREE WEEKS IN PATIENTS WITH METASTATIC REFRACTORY SOLID TUMORS-